Improving hard palate wound healing using immune modulatory autotherapies

Abstract: Improving Wound Healing Using α-gal: Antibody Stimulated Macrophage Directed Wound Healing

Materials and Methods: Our study prospectively evaluates outcomes in 9 patients treated with the “SUFA” technique (Subcision and Fat Grafting) for debilitating contracted burn scars limiting range of motion. Results are evaluated clinically with the Vancouver scale and by range of motion through the affected joints at 1, 3, 6 and 12 months. Scientific validation of the outcomes is performed eva...

Angiomyoma of the Hard Palate

Leiomyoma is a rare benign neoplasm deriving from smooth muscle. Vascular leiomyoma is its most common subtype in the oral cavity. It may appear at any age with the greatest incidence in the 4th and 5th decade of life. The common manifestation is a slow-growing, asymptomatic, submucousal mass. The diagnosis is only through microscopic examination requiring special staining...

Myofibroblasts in palatal wound healing: prospects for the reduction of wound contraction after cleft palate repair.

The surgical closure of orofacial clefts is considered to impair maxillary growth and dento-alveolar development. Wound contraction and subsequent scar tissue formation, during healing of these surgical wounds, contribute largely to these growth disturbances. The potential to minimize wound contraction and subsequent scarring by clinical interventions depends on the surgeon's knowledge of the e...

Wound complexity and healing Psychosocial factors and delayed healing Economic burden of hard-to-heal wounds

Diazoxide accelerates wound healing by improving EPC function.

Endothelial cell dysfunction is the primary cause of microvascular complications in diabetes. Diazoxide enables beta cells to rest by reversibly suppressing glucose-induced insulin secretion by opening ATP-sensitive K+ channels in the beta cells. This study investigated the role of diazoxide in wound healing in mice with streptozotocin (STZ)-induced diabetes and explored the possible mechanisms...